The Agency for Healthcare Research and Quality (AHRQ) has released a Toolkit for Preventing CLABSI and CAUTI in ICUs that offers customizable tools and training resources to prevent central line-associated bloodstream infections (CLABSI) and catheter-associated urinary tract infections (CAUTI) in intensive care units (ICUs). The toolkit is designed to help facilities assess current clinical and safety practices, implement a reduction plan, and overcome challenges in infection reduction efforts. The toolkit also includes a Playbook on how to apply AHRQ’s Comprehensive Unit-based Safety Program to prevent CLABSI and CAUTI by adjusting ICU policies and procedures.